abstract：AIM:The results of previous studies regarding the role of adiponectin in the pathogenesis of osteoarthritis (OA) are controversial. The aim of this study is to investigate the relation of plasma adiponectin levels with clinical and radiological disease severity in knee OA patients. METHOD:Sixty patients with knee OA a...

journal_title：International journal of rheumatic diseases

authors： Cuzdan Coskun N,Ay S,Evcik FD,Oztuna D

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:Australia has one of the highest prevalence rates of systemic sclerosis (SSc) worldwide. In order to highlight management deficiencies and key areas for further research, it is essential to understand its local epidemiological patterns, natural history, prognosis and mortality trends over time. METHODS:To id...

journal_title：International journal of rheumatic diseases

authors： Morrisroe K,Stevens W,Proudman S,Nikpour M

更新日期：2017-11-01 00:00:00

abstract：AIM:Genetic factors have a substantial contribution to the pathogenesis of rheumatoid arthritis (RA). Single nucleotide polymorphisms of NLRP3 p.Q705K and CARD8 p.C10X are two gene mutations that have been linked to many diseases. Here we carried out a meta-analysis to identify their association with susceptibility to ...

journal_title：International journal of rheumatic diseases

authors： Yang Z,Cao J,Yang Q,Zhang Y,Han L

更新日期：2017-10-01 00:00:00

abstract：AIM:Peroxisome proliferator-activated receptor gamma (PPARγ) agonists have anti-inflammatory properties that reduce inflammatory cytokine production in rheumatoid arthritis (RA). Cysteine-rich angiogenic inducer 61 (Cyr61) is associated with diseases related to chronic inflammation. The aim of this study was to investi...

journal_title：International journal of rheumatic diseases

authors： Kwon EJ,Park EJ,Choi S,Kim SR,Cho M,Kim J

更新日期：2017-10-01 00:00:00

abstract：AIM:To assess the psychometric properties of the Japanese version of the Revised Fibromyalgia Impact Questionnaire (JFIQR) in fibromyalgia (FM) patients. METHOD:The reliability and validity of the JFIQR were assessed using online data collected from Japanese FM patients. Reliability was evaluated based on test-retest ...

journal_title：International journal of rheumatic diseases

authors： Isomura T,Nakamura I,Kawaguchi M,Sato E,Inuzuka K,Osada K,Nishioka K,Hayakawa K

更新日期：2017-09-01 00:00:00

abstract：AIM:In June 2015, the Thai Rheumatism Association (TRA) approved an update of its recommendation for the use of biologic disease-modifying anti-rheumatic drugs (bDMARDs) and targeted synthetic (tsDMARD) in the treatment of rheumatoid arthritis (RA) to cover those currently available in Thailand (etanercept, infliximab,...

journal_title：International journal of rheumatic diseases

authors： Louthrenoo W,Kasitanon N,Katchamart W,Aiewruengsurat D,Chevaisrakul P,Chiowchanwisawakit P,Dechanuwong P,Hanvivadhanakul P,Mahakkanukrauh A,Manavathongchai S,Muangchan C,Narongroeknawin P,Phumethum V,Siripaitoon B,Suesuwan A

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Pulmonary arterial hypertension (PAH) is a major cause of mortality in connective tissue disease (CTD). The survival rates and mortality-predictive factors of a nationwide registry of Korean patients with CTD-PH measured by echocardiography were determined. METHODS:Patients with CTD-PH were enrolled between...

journal_title：International journal of rheumatic diseases

authors： Kang KY,Jeon CH,Choi SJ,Yoon BY,Choi CB,Lee CH,Suh CH,Lee CW,Cho CS,Nam EJ,Koh EM,Kim HY,Choi HJ,Kim HA,Jun JB,Lee J,Kim J,Ji JD,Min JK,Kim KJ,Shin K,So MW,Kwon SR,Kim SK,Nah SS,Kwok SK,Lee SK,Lee SW

更新日期：2017-09-01 00:00:00

abstract：PURPOSE:To conduct a systematic review and meta-analysis assessing the prevalence of metabolic syndrome (MetS) in patients with systemic lupus erythematosus (SLE) and the association between SLE and MetS. METHOD:A database search of PubMed, the Cochrane Library, EMBASE, China National Knowledge Infrastructure (CNKI), ...

journal_title：International journal of rheumatic diseases

authors： Sun C,Qin W,Zhang YH,Wu Y,Li Q,Liu M,He CD

更新日期：2017-08-01 00:00:00

abstract：AIM:The aim of this study was to evaluate the therapeutic effect of a traditional Chinese medicine (TCM), Bushen-Jianpi-Huoxue decoction (BJHD), on diabetic osteoporosis (DOP) and the action mechanisms likely mediated by nuclear factor-kappa B (NF-κB) and Wnt signaling pathways. METHODS:Fifty-five male Wistar rats wer...

journal_title：International journal of rheumatic diseases

authors： Zhang Y,Liu M,Li H,Chen Z,Liang N,Xu J,Zhang X,Zhang Y

更新日期：2017-08-01 00:00:00

abstract：AIM:The objective of this study was to assess arthritis of the whole body before and after total knee arthroplasty (TKA) in patients with rheumatoid arthritis (RA) using positron emission tomography (PET). METHOD:Seventeen knees of 17 RA patients (median age 68 years) who underwent TKA were included in this study. Cli...

journal_title：International journal of rheumatic diseases

authors： Yonemoto Y,Okamura K,Kaneko T,Okura C,Kobayashi T,Suto T,Tsushima Y,Takagishi K

更新日期：2017-06-01 00:00:00

abstract：AIM AND OBJECTIVE:To evaluate the association between ultrasonographic findings of inflammation (effusion, synovitis) and clinical findings in patients with primary painful knee osteoarthritis. METHOD:This cross-sectional study was performed on 142 patients with primary painful knee osteoarthritis (American College of...

journal_title：International journal of rheumatic diseases

authors： Abbasi B,Pezeshki-Rad M,Akhavan R,Sahebari M

更新日期：2017-05-01 00:00:00

abstract：AIM:To explain the missing heritability after the genome-wide association studies era, sequencing studies allow the identification of low-frequency variants with a stronger effect on disease risk. Common variants in the interleukin 10 gene (IL10) have been consistently associated with Behçet's disease (BD) and the goal...

journal_title：International journal of rheumatic diseases

authors： Matos M,Xavier JM,Abrantes P,Sousa I,Rei N,Davatchi F,Shahram F,Jesus G,Barcelos F,Vedes J,Salgado M,Abdollahi BS,Nadji A,Moraes-Fontes MF,Shafiee NM,Ghaderibarmi F,Vaz Patto J,Crespo J,Oliveira SA

更新日期：2017-05-01 00:00:00

abstract：AIM:Many randomized controlled trials have been performed on the efficacy and mechanism of action of omega-3 polyunsaturated fatty acids (n-3 PUFAs) on psoriasis. However, contradictory results have been obtained. This study wants to assess the effects of n-3 PUFAs on the severity of psoriasis. METHODS:The Cochrane Ce...

journal_title：International journal of rheumatic diseases

authors： Upala S,Yong WC,Theparee T,Sanguankeo A

更新日期：2017-04-01 00:00:00

abstract：:Even though, Hippocrates recognized gout as an affection of older men and a product of high living long back in 5th century BC, this painful condition promises to accompany humanity to the 21st century. The incidence is progressively rising and females are also affected in the modern era. There are also regional and e...

journal_title：International journal of rheumatic diseases

authors： Paul BJ,James R

更新日期：2017-04-01 00:00:00

abstract：:Vemurafenib is an inhibitor of the BRAF V600E mutation which is associated with tumor responses in patients with metastatic melanoma. Although it is generally well tolerated, common side effects of vemurafenib have been reported. Arthralgia is one of the more common adverse event associated with vemurafenib. We herein...

journal_title：International journal of rheumatic diseases

authors： Babacan T,Türkbeyler IH,Balakan O,Pehlivan Y,Suner A,Kısacık B

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To determine serum levels and histopathological characteristics of fatty acid binding protein 3 (FABP3) in patients with polymyositis (PM) and dermatomyositis (DM), and to evaluate the correlation between the FABP3 and muscle strength. METHODS:The study population included 24 subjects with PM/DM, 12 subjects...

journal_title：International journal of rheumatic diseases

authors： Zhang L,Zhou H,Peng Q,Jiang W,Qiao W,Wang G

更新日期：2017-02-01 00:00:00

abstract：:Several lines of research indicate that osteoarthritis (OA) is not only a joint disorder associated with mechanical stress and aging but also a 'metabolic syndrome' in which several risk factors work together to contribute to disease initiation and/or development. One such metabolic risk factor could be high cholester...

journal_title：International journal of rheumatic diseases

authors： Farnaghi S,Crawford R,Xiao Y,Prasadam I

更新日期：2017-02-01 00:00:00

abstract：AIM:There is significant autoantibody production in systemic lupus erythematosus (SLE) and scleroderma (SSc); microchimerism is also thought to play a role in pathogenesis. We determined the frequency of anti-HLA antibodies in SLE and SSc patients and evaluated associated clinical factors. METHODS:We included 77 SLE p...

journal_title：International journal of rheumatic diseases

authors： Tozkir H,Pamuk ON,Duymaz J,Gurkan H,Yazar M,Sari G,Tanrikulu H,Pamuk GE

更新日期：2016-12-01 00:00:00

abstract：AIM:Numerous epidemiologic studies have evaluated the association between overweight and hand osteoarthritis; However, the existing results are inconsistent. METHODS:Systematic searches were performed and reference lists from the retrieved trials were searched. This meta-analysis and meta-regression was executed to id...

journal_title：International journal of rheumatic diseases

authors： Jiang L,Xie X,Wang Y,Wang Y,Lu Y,Tian T,Chu M,Shen Y

更新日期：2016-12-01 00:00:00

abstract：:Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). Here, the safety and efficacy data from five Phase 2 studies of tofacitinib in patients with RA are summarized. Tofacitinib 1-30 mg twice daily was investigated, as monotherapy and in combination with methotrexate, in patient...

journal_title：International journal of rheumatic diseases

authors： Fleischmann R,Kremer J,Tanaka Y,Gruben D,Kanik K,Koncz T,Krishnaswami S,Wallenstein G,Wilkinson B,Zwillich SH,Keystone E

更新日期：2016-12-01 00:00:00

abstract：AIM:To determine the outcomes of juvenile idiopathic arthritis (JIA) in Thai children. METHODS:A retrospective cohort study. All JIA patients in a rheumatology clinic, Ramathibodi Hospital, between July 1997 and December 2012 were enrolled. The patient data were reviewed from medical records. At the most recent follow...

journal_title：International journal of rheumatic diseases

authors： Vilaiyuk S,Soponkanaporn S,Jaovisidha S,Benjaponpitak S,Manuyakorn W

更新日期：2016-12-01 00:00:00

abstract：:Retroperitoneal fibrosis (RPF) is a rare disease characterized by chronic, nonspecific inflammatory and sclerotic or fibrotic tissue in the periaortic or periiliac retroperitoneum that encases adjacent structures. There will be a series of clinical manifestations once the proliferated fibrous tissues encase the abdomi...

journal_title：International journal of rheumatic diseases

authors： Lian L,Wang C,Tian JL

更新日期：2016-11-01 00:00:00

abstract：:Leprosy is a chronic granulomatous infection caused by Mycobacterium leprae with predominant involvement of skin and nerves. We present a 70-year-old man with leprosy whose initial presentation resembled rheumatologic disease, due to leprae reaction. He presented with an 8-week history of worsening neuropathic pain in...

journal_title：International journal of rheumatic diseases

authors： Baharuddin H,Taib T,Zain MM,Ch'ng S

更新日期：2016-10-01 00:00:00

abstract：:Gynceological involvement in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides is rare. We describe a case of ANCA-associated vasculitis in an elderly woman presenting with fevers, cough and a rash. Further investigations revealed vasculitic involvement of the ovaries, fallopian tubes, uterus and omen...

journal_title：International journal of rheumatic diseases

authors： Sukhdeo A,Bertouch J

更新日期：2016-09-01 00:00:00

abstract：AIM:To assess the serum levels of soluble toll-like receptor (sTLR2) as an endogenous negative regulator of TLR2 signaling in systemic lupus erythematosus (SLE) patients, to investigate the correlation between sTLR2 and SLE disease activity index (SELDAI), SLE-related cardiovascular risk factors and ventricular dysfunc...

journal_title：International journal of rheumatic diseases

authors： Houssen ME,El-Mahdy RH,Shahin DA

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:To determine if showing patients with rheumatoid arthritis (RA) ultrasound (US) images of their inflamed joints: (i) increased belief in the necessity of medication; (ii) encouraged patient activation, that is, confidence and understanding in managing their health; and (iii) facilitated medication adherence. ...

journal_title：International journal of rheumatic diseases

authors： Joplin SK,van der Zwan R,Bagga H,Joshua F,Wong PK

更新日期：2016-07-01 00:00:00

abstract：AIM:Systemic lupus erythematosus (SLE) presents as the abnormal activation and over-proliferation of immune competent cells. Few studies have characterized the role of natural killer (NK) and NK T (NKT) cells in the pathogenesis of SLE, and therefore a consensus has not been reached as yet. METHOD:Thirty-two patients ...

journal_title：International journal of rheumatic diseases

authors： Ye Z,Ma N,Zhao L,Jiang ZY,Jiang YF

更新日期：2016-06-01 00:00:00

abstract：AIM:Nonspecific chronic synovitis of the knee joint was reported by Pollard in 1962 and its pathogenesis is considered to be a physiological reaction to intra-articular disease. In this study, we evaluated the pathological findings of the synovium of early osteoarthritis (OA)-affected knee joints with hydrarthrosis in ...

journal_title：International journal of rheumatic diseases

authors： Kurose R,Kakizaki H,Akimoto H,Yagihashi N,Sawai T

更新日期：2016-05-01 00:00:00

abstract：AIM:Procalcitonin is a marker of bacterial and fungal infection and sepsis. The present study evaluated the relationship between serum procalcitonin levels and disease activity in patients with ankylosing spondylitis (AS). METHOD:A total of 61 patients who met the 1984 New York criteria for AS were studied. Twenty-fou...

journal_title：International journal of rheumatic diseases

authors： Ozmen M,Oktay E,Tarhan EF,Aslan O,Oflazoglu U,Koseoglu MH

更新日期：2016-05-01 00:00:00

abstract：AIM:Systemic sclerosis (SSc) is characterized by immune abnormalities, progressive fibrosis of the skin and internal organs, and microvascular injury and damage. Interleukin-21 receptor (IL-21R) is expressed in the epidermis from patients with SSc. However, information describing the role of IL-21 in SSc is limited. M...

journal_title：International journal of rheumatic diseases

authors： Lei L,He ZY,Zhao C,Sun XJ,Zhong XN

更新日期：2016-04-01 00:00:00

abstract：AIM:To evaluate the efficacy of tumor necrosis factor inhibitor infliximab in patients with rheumatoid arthritis (RA) who were disease-resistant to recombinant human interleukin-1 receptor antagonist (IL-1Ra). METHODS:A total of 104 patients with active RA despite methotrexate (MTX) treatment were enrolled in the open...

journal_title：International journal of rheumatic diseases

authors： Bao J,Yue T,Li T,He DY,Bao YX

更新日期：2016-04-01 00:00:00

abstract：AIM:This study was designed to examine the effect of Burdock root tea on inflammatory markers and oxidative stress indicators in patients with knee osteoarthritis (OA). METHODS:Thirty-six patients (10 men and 26 women) aged 50-70 years old with knee osteoarthritis referred to the Physical Medicine and Rehabilitation D...

journal_title：International journal of rheumatic diseases

authors： Maghsoumi-Norouzabad L,Alipoor B,Abed R,Eftekhar Sadat B,Mesgari-Abbasi M,Asghari Jafarabadi M

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:To determine the effect of peer-led group education on the quality of life and depression in patients with ankylosing spondylitis (AS). METHODS:Eighty patients with definite AS were allocated randomly to either the education or control group. The education group (n = 40) was subjected to a peer-led group ed...

journal_title：International journal of rheumatic diseases

authors： Kaya T,Goksel Karatepe A,Atici Ozturk P,Gunaydin R

更新日期：2016-02-01 00:00:00

abstract：AIM:The aim of this article is two-fold: (i) to demonstrate the relation between vitamin D deficiency and dry eye and impaired tear function; and (ii) to investigate the possible associations among clinical parameters of hypovitaminosis D with dry eye parameters. METHOD:Fifty premenopausal women with vitamin D deficie...

journal_title：International journal of rheumatic diseases

authors： Yildirim P,Garip Y,Karci AA,Guler T

更新日期：2016-01-01 00:00:00

abstract：AIM:To analyze the clinical features, outcomes and prognosis of neonatal lupus erythematosus (NLE) in China. METHOD:We reviewed 12 NLE cases at the Peking Union Medical College Hospital and compared the data with 111 cases reported in China between 1990 and 2014. The Chinese medical journal search engines used in this...

journal_title：International journal of rheumatic diseases

authors： Li YQ,Wang Q,Luo Y,Zhao Y

更新日期：2015-09-01 00:00:00

abstract：:Primary systemic vasculitis is a group of heterogeneous disorders, characterized by inflammation of blood vessels causing end organ damage from ischemia, aneurysm formation or dissection. Delay in the early diagnosis owing to non-specific symptoms, lack of definitive serological tests, limited availability of biopsy a...

journal_title：International journal of rheumatic diseases

authors： Danve A,O'Dell J

更新日期：2015-09-01 00:00:00

abstract：AIM:In rheumatoid arthritis (RA) hands, we applied high-resolution peripheral quantitative computed tomography (HR-pQCT) and 3 Tesla (3 T) magnetic resonance imaging (MRI), which are new methods for erosion detection and bone marrow edema (BME) quantification. We compared the erosion measurements between these techniqu...

journal_title：International journal of rheumatic diseases

authors： Lee CH,Srikhum W,Burghardt AJ,Virayavanich W,Imboden JB,Link TM,Li X

更新日期：2015-07-01 00:00:00

abstract：AIM:To compare the Disease Activity Score with 28 joint (DAS28) using erythrocyte sedimentation rate (ESR) (DAS28-ESR) and DAS28 using C-reactive protein (CRP) (DAS28-CRP) with thresholds validated for DAS28-ESR in Turkish patients with rheumatoid arthritis. METHOD:The DAS28 data of 112 patients with rheumatoid arthri...

journal_title：International journal of rheumatic diseases

authors： Sengul I,Akcay-Yalbuzdag S,Ince B,Goksel-Karatepe A,Kaya T

更新日期：2015-07-01 00:00:00

abstract：:Exposure to cadmium links smoking, the most import antetiological factor in the development of seropositive RA, and many of the other known contemporary risk factors. Epidemiological studies investigating the link between smoking, occupations, social class, region of residency and RA should consider cadmium exposure a...

journal_title：International journal of rheumatic diseases

authors： Hutchinson D

更新日期：2015-06-01 00:00:00

abstract：AIM:Some studies have been performed to elucidate the association between Fc gamma receptor 3B (FCGR3B) copy number (CN) and the risk of systemic lupus erythematosus (SLE) and/or lupus nephritis (LN), yet the results remain conflicting. Therefore, we have undertaken a systematic review of all the studies published and ...

journal_title：International journal of rheumatic diseases

authors： Yuan J,Zhao D,Wu L,Xu X,Pang Y,Zhang J,Ma Y,Liu J,Wang J

更新日期：2015-05-01 00:00:00